Development and validation of nanostructured medicated biomaterials for the treatment and regeneration of metastatic bone tissue

The project aims to develop and validate medicated biomimetic devices starting from cutting-edge technologies in the tissue regeneration sector, including porous implants with hierarchically organized structure and morphological-structural and biomechanical characteristics of natural bone, calcium-based injectable pastes. phosphates mixed with natural polymers, and implants derived from biomorphic transformation processes with unique structural properties. The final objective will be the validation of the devices, and specifically their capacity for integration, osteosynthesis and treatment of tumor cells, in ex vivo bone metastasis samples.

Coordinator: Istituto Scientifico Romagnolo per lo studio e la cura dei tumori – IRST – IRCCS Partner: CIRI Science della Vita e Tecnologie per la Salute (Università di Bologna), Istec CNR, Istituto Ortopedico Rizzoli, TPM – Fondazione Democenter – SIPE 

Enterprises: GreenBone Ortho, Fin-Ceramica Faenza, Rigenerand 

Collaborations: CERR – Confindustria Emilia Romagna Ricerca 

Regione Emilia-Romagna Funding: 799.958,80 euro 

Project duration: from 19/07/2019 to 18/02/2022 (31 months) 

Call: Strategic industrial research projects aimed at S3 priority areas

Main value chains involved: Biomedical, Pharmaceutical, Chemical, Biological, Clinical

Web site: http://dinamica.study-project.eu/